TNFSF13B (Human) Recombinant Protein
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Specification
Product Description
Human TNFSF13B (Q9Y275, 134 a.a. - 285 a.a.) recombinant protein with His-tag at N-terminal expressed in Nicotiana benthamiana expression system.
Sequence
HHHHHHHHHHAVQGPEETVTQDCLQLIADSETPTIQKGSYTFVPWLLSFKRGSALEEKENKILVKETGYFFIYGQVLYTDKTYAMGHLIQRKKVHVFGDELSLVTLFRCIQNMPETLPNNSCYSAGIAKLEEGDELQLAIPRENAQISLDGDVTFFGALKLL.
Host
Nicotiana benthamiana
Theoretical MW (kDa)
18-20
Form
Lyophilized
Preparation Method
Nicotiana benthamiana plant
Purity
> 97% by SDS-PAGE
Activity
The activity is determined by dose-dependent stimulation of proliferation B cell from Human PBMC. Cell proliferation was measured by MTT method.
activity results may vary with PBMC donors.Storage Buffer
Lyophilized from 20 mM PBS buffer pH 7 and 0.2 M NaCl.
Storage Instruction
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles. -
Applications
Functional Study
SDS-PAGE
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Gene Info — TNFSF13B
Entrez GeneID
10673Protein Accession#
Q9Y275Gene Name
TNFSF13B
Gene Alias
BAFF, BLYS, CD257, DTL, TALL-1, TALL1, THANK, TNFSF20, ZTNF4
Gene Description
tumor necrosis factor (ligand) superfamily, member 13b
Omim ID
603969Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. [provided by RefSeq
Other Designations
ApoL related ligand TALL-1|B-cell activating factor|B-lymphocyte stimulator|OTTHUMP00000018691|TNF and ApoL-related leukocyte expressed ligand 1|TNF homolog that activates apoptosis|delta BAFF|dendritic cell-derived TNF-like molecule|tumor necrosis factor
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