SIRPG (Human) Recombinant Protein
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More Files
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Result of bioactivity analysis
Result of bioactivity analysis
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Specification
Product Description
Human SIRPG (Q9P1W8, 29 a.a. - 360 a.a.) partial length recombinant protein hIgG-His tag expressed in Baculovirus expression system.
Sequence
EEELQMIQPEKLLLVTVGKTATLHCTVTSLLPVGPVLWFRGVGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRISSITPADVGTYYCVKFRKGSPENVEFKSGPGTEMALGAKPSAPVVLGPAARTTPEHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPTGQSVAYSIRSTARVVLDPWDVRSQVICEVAHVTLQGDPLRGTANLSEAIRVPPTLEVTQQPMRVGNQVNVTCQVRKFYPQSLQLTWSENGNVCQRETASTLTENKDGTYNWTSWFLVNISDQRDDVVLTCQVKHDGQLAVSKRLALEVTVHQKDQSSDATP
Host
Viruses
Theoretical MW (kDa)
64
Form
Liquid
Preparation Method
Baculovirus expression system
Purity
> 90% by SDS-PAGE
Endotoxin Level
< 1 EU per 1 ug of protein (determined by LAL method)
Activity
Measured by the binding ability in a functional ELISA with Human CD47.
Quality Control Testing
3 ug by SDS-PAGE under reducing condition and visualized by Coomassie blue stain.
Storage Buffer
In Phosphate-Buffer Saline pH 7.4 (40% glycerol)
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.Note
Result of bioactivity analysis
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Applications
Functional Study
SDS-PAGE
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Gene Info — SIRPG
Entrez GeneID
55423Protein Accession#
Q9P1W8Gene Name
SIRPG
Gene Alias
CD172g, SIRP-B2, SIRPB2, SIRPgamma, bA77C3.1
Gene Description
signal-regulatory protein gamma
Omim ID
605466Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq
Other Designations
CD172g antigen|OTTHUMP00000030000|OTTHUMP00000185041|SIRP beta 2|signal-regulatory protein beta 2
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