APOL1 monoclonal antibody, clone CL0171
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human APOL1.
Immunogen
Recombinant protein corresponding to human APOL1.
Epitope
This antibody binds to an epitope located within the peptide sequence AEELKKVAQELEEKL as determined by overlapping synthetic peptides.
Sequence
SNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELKKVAQELEEKLNILNN
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG1
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:2500-1:5000)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western Blot analysis of human plasma tissue lysate with APOL1 monoclonal antibody, clone CL0171 (Cat # MAB15549).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lung with APOL1 monoclonal antibody, clone CL0171 (Cat # MAB15549) shows plasma positivity. -
Gene Info — APOL1
Entrez GeneID
8542Protein Accession#
O14791Gene Name
APOL1
Gene Alias
APO-L, APOL, APOL-I
Gene Description
apolipoprotein L, 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000028705|apolipoprotein L-I|apolipoprotein L1
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Interactome
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Disease
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