PDPN monoclonal antibody, clone PDPN/1433
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human PDPN.
Immunogen
Recombinant protein corresponding to amino acids 24-126 of human PDPN.
Host
Mouse
Theoretical MW (kDa)
38-43
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells)
Immunofluorescence (0.5-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
Western Blotting (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS.
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human uterine cervix with PDPN monoclonal antibody, clone PDPN/1433 (Cat # MAB14725).Immunofluorescence
Flow Cytometry
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Gene Info — PDPN
Entrez GeneID
10630Protein Accession#
Q86YL7Gene Name
PDPN
Gene Alias
AGGRUS, GP36, GP40, Gp38, HT1A-1, OTS8, PA2.26, T1A, T1A-2
Gene Description
podoplanin
Omim ID
608863Gene Ontology
HyperlinkGene Summary
This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000009640|OTTHUMP00000044504|glycoprotein, 36-KD|hT1alpha-1|hT1alpha-2|lung type I cell membrane associated glycoprotein|lung type-I cell membrane-associated glycoprotein|lung type-I cell membrane-associated glycoprotein (T1A-2)
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Interactome
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Disease
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Publication Reference
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Lymphatic microvessel density and lymphovascular invasion assessed by anti-podoplanin immunostaining in human breast cancer.
Schoppmann SF, Birner P, Studer P, Breiteneder-Geleff S.
Anticancer Research 2001 Jul; 21(4):2351.
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Characterization and cloning of a novel glycoprotein expressed by stromal cells in T-dependent areas of peripheral lymphoid tissues.
Farr AG, Berry ML, Kim A, Nelson AJ, Welch MP, Aruffo A.
The Journal of Experimental Medicine 1992 Nov; 176(5):1477.
Application:IEM, IHC, WB-Tr, Hamster, Mouse, Monkey, Brains, COS cells, Lymph node paracortex, Spleens.
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Lymphatic microvessel density and lymphovascular invasion assessed by anti-podoplanin immunostaining in human breast cancer.
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