NCOA3 monoclonal antibody, clone 2C11B12
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant NCOA3.
Immunogen
Recombinant protein corresponding to amino acids 1-200 of human NCOA3.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis using NCOA3 monoclonal antibody, clone 2C11B12 (Cat # MAB10558) against truncated Trx-NCOA3 recombinant protein (1) and truncated NCOA3 (aa 1-200)-hIgGFc transfected CHOK1 cell lysate (2).Enzyme-linked Immunoabsorbent Assay
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Gene Info — NCOA3
Entrez GeneID
8202Gene Name
NCOA3
Gene Alias
ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, MGC141848, RAC3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP
Gene Description
nuclear receptor coactivator 3
Omim ID
601937Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein. [provided by RefSeq
Other Designations
CBP-interacting protein|OTTHUMP00000031716|OTTHUMP00000031718|amplified in breast cancer-1|receptor-associated coactivator 3|steroid receptor coactivator protein 3|thyroid hormone receptor activator molecule 1
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Interactome
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Disease
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