Anti-Eculizumab (Human) ELISA Kit (Qualitative)
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Specification
Product Description
Anti-Eculizumab (Human) ELISA Kit (Qualitative) is a qualitative determination of antibodies to Eculizumab in serum and plasma.
Suitable Sample
Serum or Plasma
Sample Volume
20 uL
Absorbance (nm)
450/650 nm
Detection Method
Colorimetric
Assay Type
Qualitative
Limit of Detection
6.25 ng/mL
Regulation Status
For research use only (RUO)
Storage Instruction
Store the kit at 4°C.
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Applications
Qualitative
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Gene Info — C5
Entrez GeneID
727Gene Name
C5
Gene Alias
CPAMD4, FLJ17816, FLJ17822, MGC142298
Gene Description
complement component 5
Omim ID
120900Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to a susceptibility to liver fibrosis and to rheumatoid arthritis. [provided by RefSeq
Other Designations
OTTHUMP00000022001|anaphylatoxin C5a analog
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