ALDH8A1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
SDS-PAGE Gel
ALDH8A1 transfected lysate.
Western Blot
Lane 1: ALDH8A1 transfected lysate ( 53.68 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-ALDH8A1 full-length
Host
Human
Theoretical MW (kDa)
53.68
Interspecies Antigen Sequence
Mouse (89)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-ALDH8A1 antibody (H00064577-B01) by Western Blots.
SDS-PAGE Gel
ALDH8A1 transfected lysate.
Western Blot
Lane 1: ALDH8A1 transfected lysate ( 53.68 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — ALDH8A1
Entrez GeneID
64577GeneBank Accession#
NM_022568.2Protein Accession#
NP_072090.1Gene Name
ALDH8A1
Gene Alias
ALDH12, DJ352A20.2, DKFZp779D2315, MGC138650
Gene Description
aldehyde dehydrogenase 8 family, member A1
Omim ID
606467Gene Ontology
HyperlinkGene Summary
This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
Other Designations
aldehyde dehydogenase 8 family, member A1|aldehyde dehydrogenase 12|aldehyde dehydrogenase 8A1|aldehyde dehydrogenase family protein
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