GREM2 (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of GREM2 transfected lysate using rabbit polyclonal anti-GREM2 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-GREM2.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (93)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of GREM2 transfected lysate using rabbit polyclonal anti-GREM2 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-GREM2.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-GREM2 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-GREM2 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — GREM2
Entrez GeneID
64388Gene Name
GREM2
Gene Alias
CKTSF1B2, DAND3, PRDC
Gene Description
gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis)
Omim ID
608832Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq
Other Designations
OTTHUMP00000037834|cysteine knot superfamily 1, BMP antagonist 2|gremlin 2|protein related to DAN and cerberus
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Interactome
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Disease
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