ICOS rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ICOS peptide using ARM Technology.
Immunogen
A synthetic peptide of human ICOS is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ICOS peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — ICOS
Entrez GeneID
29851GeneBank Accession#
ICOSGene Name
ICOS
Gene Alias
AILIM, CD278, MGC39850
Gene Description
inducible T-cell co-stimulator
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. [provided by RefSeq
Other Designations
activation-inducible lymphocyte immunomediatory molecule|inducible costimulator
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