QPCT monoclonal antibody (M02), clone 3G2
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant QPCT.
Immunogen
QPCT (NP_036545, 262 a.a. ~ 359 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PNSARWFERLQAIEHELHELGLLKDHSLEGRYFQNYSYGGVIQDDHIPFLRRGVPVLHLIPSPFPEVWHTMDDNEENLDESTIDNLNKILQVFVLEYL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (82); Rat (69)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to QPCT on formalin-fixed paraffin-embedded human breast cancer. [antibody concentration 3 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged QPCT is 0.1 ng/ml as a capture antibody.ELISA
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Gene Info — QPCT
Entrez GeneID
25797GeneBank Accession#
NM_012413Protein Accession#
NP_036545Gene Name
QPCT
Gene Alias
GCT, QC
Gene Description
glutaminyl-peptide cyclotransferase
Omim ID
607065Gene Ontology
HyperlinkGene Summary
This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase. [provided by RefSeq
Other Designations
glutaminyl cyclase
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Interactome
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Disease
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