TNFSF18 monoclonal antibody (M01), clone 6F7
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TNFSF18.
Immunogen
TNFSF18 (NP_005083, 68 a.a. ~ 177 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KWQMASSEPPCVNKVSDWKLEILQNGLYLIYGQVAPNANYNDVAPFEVRLYKNKDMIQTLTNKSKIQNVGGTYELHVGDTIDLIFNSEHQVLKNNTYWGIILLANPQFIS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (51)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged TNFSF18 is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — TNFSF18
Entrez GeneID
8995GeneBank Accession#
NM_005092Protein Accession#
NP_005083Gene Name
TNFSF18
Gene Alias
AITRL, GITRL, MGC138237, TL6, hGITRL
Gene Description
tumor necrosis factor (ligand) superfamily, member 18
Omim ID
603898Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq
Other Designations
AITR ligand|GITR ligand|glucocorticoid-induced TNFR-related protein ligand
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