TUB (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human TUB partial ORF ( NP_003311, 439 a.a. - 538 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
KMSVIVPGMNMVHERVSIRPRNEHETLLARWQNKNTESIIELQNKTPVWNDDTQSYVLNFHGRVTQASVKNFQIIHGNDPDYIVMQFGRVAEDVFTMDYN
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TUB
Entrez GeneID
7275GeneBank Accession#
NM_003320Protein Accession#
NP_003311Gene Name
TUB
Gene Alias
rd5
Gene Description
tubby homolog (mouse)
Omim ID
601197Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
Other Designations
tubby|tubby homologue
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Interactome
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Disease
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