PFKFB2 MaxPab rabbit polyclonal antibody (D01)
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More Files
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Immunoprecipitation
Immunoprecipitation of PFKFB2 transfected lysate using anti-PFKFB2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with PFKFB2 purified MaxPab mouse polyclonal antibody (B01P) (H00005208-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PFKFB2 protein.
Immunogen
PFKFB2 (NP_006203.2, 1 a.a. ~ 505 a.a) full-length human protein.
Sequence
MSGASSSEQNNNSYETKTPNLRMSEKKCSWASYMTNSPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMILNFAEQNSFKVFFVESVCDDPDVIAANILEVKVSSPDYPERNRENVMEDFLKRIECYKVTYRPLDPDNYDKDLSFIKVINVGQRFLVNRVQDYIQSKIVYYLMNIHVQPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQEITDLKVWTSQLKRTIQTAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYGCKVETIKLNVEAVNTHRDKPTNNFPKNQTPVRMRRNSFTPLSSSNTIRRPRNYSVGSRPLKPLSPLRAQDMQEGAD
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (93); Rat (95)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Immunoprecipitation
Immunoprecipitation of PFKFB2 transfected lysate using anti-PFKFB2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with PFKFB2 purified MaxPab mouse polyclonal antibody (B01P) (H00005208-B01P). -
Gene Info — PFKFB2
Entrez GeneID
5208GeneBank Accession#
NM_006212.2Protein Accession#
NP_006203.2Gene Name
PFKFB2
Gene Alias
DKFZp781D2217, MGC138308, MGC138310, PFK-2/FBPase-2
Gene Description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
Omim ID
171835Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
Other Designations
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2|6PF-2-K/Fru-2,6-P2ASE heart-type isozyme|OTTHUMP00000034285|OTTHUMP00000034286|PFKFB, cardiac|fructose-2,6-bisphosphatase, cardiac isozyme
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Interactome
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Pathway
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Disease
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