NPHS1 monoclonal antibody (M02), clone 3H6
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant NPHS1.
Immunogen
NPHS1 (NP_004637.1, 33 a.a. ~ 122 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
GFWALPENLTVVEGASVELRCGVSTPGSAVQWAKDGLLLGPDPRIPGFPRYRLEGDPARGEFHLHIEACDLSDDAEYECQVGRSEMGPEL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (83); Rat (81)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.64 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — NPHS1
Entrez GeneID
4868GeneBank Accession#
NM_004646Protein Accession#
NP_004637.1Gene Name
NPHS1
Gene Alias
CNF, NPHN
Gene Description
nephrosis 1, congenital, Finnish type (nephrin)
Gene Ontology
HyperlinkGene Summary
Nephrin is a kidney glomerular filtration barrier protein that is an essential component of the interpodocyte-spanning slit diaphragm. Mutations in the nephrin gene are associated with congenital nephrotic syndrome (NPHS1; MIM 256300).[supplied by OMIM
Other Designations
nephrin|renal glomerulus-specific cell adhesion receptor
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Interactome
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Disease
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