MCC MaxPab rabbit polyclonal antibody (D01)
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human MCC protein.
Immunogen
MCC (NP_002378.1, 1 a.a. ~ 829 a.a) full-length human protein.
Sequence
MNSGVAMKYGNDSSAELSELHSAALASLKGDIVELNKRLQQTERERDLLEKKLAKAQCEQSHLMREHEDVQERTTLRYEERITELHSVIAELNKKIDRLQGTTIREEDEYSELRSELSQSQHEVNEDSRSMDQDQTSVSIPENQSTMVTADMDNCSDLNSELQRVLTGLENVVCGRKKSSCSLSVAEVDRHIEQLTTASEHCDLAIKTVEEIEGVLGRDLYPNLAEERSRWEKELAGLREENESLTAMLCSKEEELNRTKATMNAIREERDRLRRRVRELQTRLQSVQATGPSSPGRLTSTNRPINPSTGELSTSSSSNDIPIAKIAERVKLSKTRSESSSSDRPVLGSEISSIGVSSSVAEHLAHSLQDCSNIQEIFQTLYSHGSAISESKIREFEVETERLNSRIEHLKSQNDLLTITLEECKSNAERMSMLVGKYESNATALRLALQYSEQCIEAYELLLALAESEQSLILGQFRAAGVGSSPGDQSGDENITQMLKRAHDCRKTAENAAKALLMKLDGSCGGAFAVAGCSVQPWESLSSNSHTSTTSSTASSCDTEFTKEDEQRLKDYIQQLKNDRAAVKLTMLELESIHIDPLSYDVKPRGDSQRLDLENAVLMQELMAMKEEMAELKAQLYLLEKEKKALELKLSTREAQEQAYLVHIEHLKSEVEEQKEQRMRSLSSTSSGSKDKPGKECADAASPALSLAELRTTCSENELAAEFTNAIRREKKLKARVQELVSALERLTKSSEIRHQQSAEFVNDLKRANSNLVAAYEKAKKKHQNKLKKLESQMMAMVERHETQVRMLKQRIALLEEENSRPHTNETSL
Host
Rabbit
Reactivity
Human, Mouse, Rat
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
MCC MaxPab rabbit polyclonal antibody. Western Blot analysis of MCC expression in rat brain.Western Blot (Tissue lysate)
MCC MaxPab rabbit polyclonal antibody. Western Blot analysis of MCC expression in mouse lung.Western Blot (Transfected lysate)
Western Blot analysis of MCC expression in transfected 293T cell line (H00004163-T01) by MCC MaxPab polyclonal antibody.
Lane 1: MCC transfected lysate(93.1 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of MCC transfected lysate using anti-MCC MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with MCC purified MaxPab mouse polyclonal antibody (B01P) (H00004163-B01P). -
Gene Info — MCC
Entrez GeneID
4163GeneBank Accession#
NM_002387.1Protein Accession#
NP_002378.1Gene Name
MCC
Gene Alias
DKFZp762O1615, FLJ38893, FLJ46755, MCC1
Gene Description
mutated in colorectal cancers
Omim ID
159350Gene Ontology
HyperlinkGene Summary
This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
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Interactome
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Disease
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