IL2RB purified MaxPab mouse polyclonal antibody (B01P)
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Specifications
Product Description
Mouse polyclonal antibody raised against a full-length human IL2RB protein.
Immunogen
IL2RB (NP_000869.1, 1 a.a. ~ 551 a.a) full-length human protein.
Sequence
MAAPALSWRLPLLILLLPLATSWASAAVNGTSQFTCFYNSRANISCVWSQDGALQDTSCQVHAWPDRRRWNQTCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEEAPLLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFTTWSPWSQPLAFRTKPAALGKDTIPWLGHLLVGLSGAFGFIILVYLLINCRNTGPWLKKVLKCNTPDPSKFFSQLSSEHGGDVQKWLSSPFPSSSFSPGGLAPEISPLEVLERDKVTQLLLQQDKVPEPASLSSNHSLTSCFTNQGYFFFHLPDALEIEACQVYFTYDPYSEEDPDEGVAGAPTGSSPQPLQPLSGEDDAYCTFPSRDDLLLFSPSLLGGPSPPSTAPGGSGAGEERMPPSLQERVPRDWDPQPLGPPTPGVPDLVDFQPPPELVLREAGEEVPDAGPREGVSFPWSRPPGQGEFRALNARLPLNTDAYLSLQELQGQDPTHLV
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (57)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Flow Cytometry
FACS analysis of negative control 293 cells (Black) and IL2RB expressing 293 cells (Green) using IL2RB purified MaxPab mouse polyclonal antibody.Western Blot (Transfected lysate)
Western Blot analysis of IL2RB expression in transfected 293T cell line (H00003560-T01) by IL2RB MaxPab polyclonal antibody.
Lane 1: IL2RB transfected lysate(60.61 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — IL2RB
Entrez GeneID
3560GeneBank Accession#
NM_000878.2Protein Accession#
NP_000869.1Gene Name
IL2RB
Gene Alias
CD122, P70-75
Gene Description
interleukin 2 receptor, beta
Omim ID
146710Gene Ontology
HyperlinkGene Summary
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq
Other Designations
CD122 antigen|OTTHUMP00000028799|high affinity IL-2 receptor beta subunit|interleukin 2 receptor beta
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Interactomes
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Pathways
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Diseases
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