IGL@ mouse monoclonal antibody (hybridoma)

Catalog # H00003535-M

Size

Price

Stock

Quantity

Size:Up to 5 Clones
Price: USD $ 3,600.00
Stock:
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
  • Specifications

    Product Description

    Mouse monoclonal antibody raised against a full-length recombinant IGL@.

    Immunogen

    IGL@ (AAH89414.1, 1 a.a. ~ 232 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    Sequence

    MAWTPLLLPLLTFCTVSEASYDLTQPPSVSVSPGQTARITCSGDALPRKYAFWYQQKSGQAPVLVIYEDSKRPSGIPERFSGSSSGTMATLTISGAQVEDEGDYYCYSTDISGYPVFGGGTKVTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWRSHKSYSCQVTHEGSTVEKTVAPTECS

    Host

    Mouse

    Reactivity

    Human

    Quality Control Testing

    Antibody reactivity and specificity confirmed by ELISA and Western Blot.

    Deliverables

    Up to 5 positive hybridoma clones will be delivered to customer in the cryotube format.

    Note

    Customer should check the viability of the hybridomas within one month from the date of receipt. Fee-for-service of long term hybridoma storage can be performed upon customer's request.

  • Applications

    Western Blot (Transfected lysate)

    Western Blot (Recombinant protein)

    ELISA

  • Gene Info — IGL@

    Entrez GeneID

    3535

    GeneBank Accession#

    BC089414.1

    Protein Accession#

    AAH89414.1

    Gene Name

    IGL@

    Gene Alias

    IGL, MGC88804

    Gene Description

    immunoglobulin lambda locus

    Gene Ontology

    Hyperlink

    Gene Summary

    Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immunoglobulin molecule consists of two identical heavy chains and two identical light chains. There are two classes of light chains, kappa and lambda. This region represents the germline organization of the lambda light chain locus. The locus includes V (variable), J (joining), and C (constant) segments. During B cell development, a recombination event at the DNA level joins a single V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase, and by somatic hypermutation, which occurs during B cell maturation in the spleen and lymph nodes. Several V segments and three C segments are known to be incapable of encoding a protein and are considered pseudogenes. The locus also includes several non-immunoglobulin genes, many of which are pseudogenes or are predicted by automated computational analysis or homology to other species. [provided by RefSeq

    Other Designations

    immunoglobulin lambda gene cluster

  • Interactomes
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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