GUCY2D monoclonal antibody (M01), clone 4E12
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More Files
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Western Blot (Tissue lysate)
GUCY2D monoclonal antibody (M01), clone 4E12. Western Blot analysis of GUCY2D expression in human spleen.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged GUCY2D is approximately 0.1ng/ml as a capture antibody.
Western Blot detection against Immunogen (37.73 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant GUCY2D.
Immunogen
GUCY2D (NP_000171, 521 a.a. ~ 630 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
RKVAQGSRSSLGARSMSDIRSGPSQHLDSPNIGVYEGDRVWLKKFPGDQHIAIRPATKTAFSKLQELRHENVALYLGLFLARGAEGPAALWEGNLAVVSEHCTRGSLQDL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (76); Rat (77)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.73 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
GUCY2D monoclonal antibody (M01), clone 4E12. Western Blot analysis of GUCY2D expression in human spleen.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged GUCY2D is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — GUCY2D
Entrez GeneID
3000GeneBank Accession#
NM_000180Protein Accession#
NP_000171Gene Name
GUCY2D
Gene Alias
CORD5, CORD6, CYGD, GUC1A4, GUC2D, LCA, LCA1, RETGC-1, ROS-GC1, retGC
Gene Description
guanylate cyclase 2D, membrane (retina-specific)
Gene Ontology
HyperlinkGene Summary
This gene encodes a retina-specific guanylate cyclase, which is a member of the membrane guanylyl cyclase family. Like other membrane guanylyl cyclases, this enzyme has a hydrophobic amino-terminal signal sequence followed by a large extracellular domain, a single membrane spanning domain, a kinase homology domain, and a guanylyl cyclase catalytic domain. In contrast to other membrane guanylyl cyclases, this enzyme is not activated by natriuretic peptides. Mutations in this gene result in Leber congenital amaurosis and cone-rod dystrophy-6 diseases. [provided by RefSeq
Other Designations
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Interactome
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