FDFT1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-FDFT1 full-length
Host
Human
Theoretical MW (kDa)
45.98
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-FDFT1 antibody (H00002222-B01) by Western Blots.
SDS-PAGE Gel
FDFT1 transfected lysate.
Western Blot
Lane 1: FDFT1 transfected lysate ( 45.98 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — FDFT1
Entrez GeneID
2222GeneBank Accession#
NM_004462.3Protein Accession#
NP_004453.3Gene Name
FDFT1
Gene Alias
DGPT, ERG9, SQS, SS
Gene Description
farnesyl-diphosphate farnesyltransferase 1
Omim ID
184420Gene Ontology
HyperlinkGene Summary
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq
Other Designations
FPP:FPP farnesyltransferase|presqualene-di-diphosphate synthase|squalene synthase
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Interactome
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Pathway
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Disease
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