DRD2 (Human) Recombinant Protein (Q01)
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More Files
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Specifications
Product Description
Human DRD2 partial ORF ( AAH21195, 1 a.a. - 110 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIF
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.73
Interspecies Antigen Sequence
Rat (96)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — DRD2
Entrez GeneID
1813GeneBank Accession#
BC021195Protein Accession#
AAH21195Gene Name
DRD2
Gene Alias
D2DR, D2R
Gene Description
dopamine receptor D2
Gene Ontology
HyperlinkGene Summary
This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq
Other Designations
dopamine receptor D2 isoform|seven transmembrane helix receptor
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Interactomes
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Pathways
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