BDKRB1 DNAxPab
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More Files
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Specifications
Product Description
Rabbit polyclonal antibody raised against a partial-length human BDKRB1 DNA using DNAx™ Immune technology.
Technology
Immunogen
BDKRB1 (NP_000701.2, 1 a.a. ~ 291 a.a) partial-length human DNA
Sequence
MASSWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICFFGLLGNLFVLLVFLLPRRQLNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGVIKANLFISIFLVVAISQDRYRVLVHPMASRRQQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQAVPDLNITACILLLPHEAWHFARIVELNILGFLLPLAAIVFFNYHILASLRTREEVSRTRCGGRKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFID
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of BDKRB1 expression in transfected 293T cell line by BDKRB1 DNAxPab polyclonal antibody.
Lane 1: BDKRB1 transfected lysate(53.13 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — BDKRB1
Entrez GeneID
623GeneBank Accession#
NM_000710.2Protein Accession#
NP_000701.2Gene Name
BDKRB1
Gene Alias
B1BKR, B1R, BKB1R, BKR1, BRADYB1
Gene Description
bradykinin receptor B1
Omim ID
600337Gene Ontology
HyperlinkGene Summary
Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. [provided by RefSeq
Other Designations
BK-1 receptor|bradykinin B1 receptor|bradykinin receptor 1
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Interactomes
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Pathways
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Diseases
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