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ELISA

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

ARG2

Gene Alias

-

Gene Description

arginase, type II

Omim ID

Gene Ontology

Gene Summary

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq

Other Designations

A-II|L-arginine amidinohydrolase|L-arginine ureahydrolase|kidney arginase|nonhepatic arginase