ABAT DNAxPab

Catalog # H00000018-W01P

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Price

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Quantity

Size:200 ug
Price: USD $ 620.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
  • Specifications

    Product Description

    Rabbit polyclonal antibody raised against a full-length human ABAT DNA using DNAx™ Immune technology.DNAx Polyclonal Antibody,DNAx Polyclonal Antibodies,DNAx Pab,DNAx Polyclonal,DNA Immune,DNA Immunization,Immune Technology,Hard-to-Find Antibody,Hard-to-Find Antibodies,Hard-to-Find,Hard to Find,HardtoFind

    Technology

    DNAx™ Immune

    Immunogen

    Full-length human DNA

    Sequence

    MASMLLAQRLACSFQHSYRLLVPGSRHISQAAAKVDVEFDYDGPLMKTEVPGPRSQELMKQLNIIQNAEAVHFFCNYEESRGNYLVDVDGNRMLDLYSQISSVPIGYSHPALLKLIQQPQNASMFVNRPALGILPPENFVEKLRQSLLSVAPKGMSQLITMACGSCSNENALKTIFMWYRSKERGQRGFSQEELETCMINQAPGCPDYSILSFMGAFHGRTMGCLATTHSKAIHKIDIPSFDWPIAPFPRLKYPLEEFVKENQQEEARCLEEVEDLIVKYRKKKKTVAGIIVEPIQSEGGDNHASDDFFRKLRDIARKHGCAFLVDEVQTGGGCTGKFWAHEHWGLDDPADVMTFSKKMMTGGFFHKEEFRPNAPYRIFNTWLGDPSKNLLLAEVINIIKREDLLNNAAHAGKALLTGLLDLQARYPQFISRVRGRGTFCSFDTPDDSIRNKLILIARNKGVVLGGCGDKSIRFRPTLVFRDHHAHLFLNIFSDILADFK

    Host

    Rabbit

    Reactivity

    Human

    Interspecies Antigen Sequence

    Mouse (91); Rat (91)

    Purification

    Protein A

    Quality Control Testing

    Antibody reactive against mammalian transfected lysate.

    Storage Buffer

    In 1x PBS, pH 7.4

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot (Transfected lysate)

    Immunofluorescence (Transfected cell)

    Flow Cytometry (Transfected cell)

  • Gene Info — ABAT

    Entrez GeneID

    18

    GeneBank Accession#

    NM_000663.3

    Protein Accession#

    NP_000654.2

    Gene Name

    ABAT

    Gene Alias

    FLJ17813, GABA-AT, GABAT, NPD009

    Gene Description

    4-aminobutyrate aminotransferase

    Omim ID

    137150

    Gene Ontology

    Hyperlink

    Gene Summary

    4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq

    Other Designations

    GABA aminotransferase|GABA transferase|gamma-amino-N-butyrate transaminase

  • Interactomes
  • Pathways
  • Diseases
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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