POLR2E recombinant monoclonal antibody, clone R05-8J5
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More Files
- More Functions
Western Blot (Cell lysate)
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human POLR2E.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human POLR2E.
Theoretical MW (kDa)
25
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity chromatography
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Cell lysate)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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Gene Info — POLR2E
Entrez GeneID
5434Protein Accession#
P19388Gene Name
POLR2E
Gene Alias
RPABC1, RPB5, XAP4, hRPB25, hsRPB5
Gene Description
polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
Omim ID
180664Gene Ontology
HyperlinkGene Summary
This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11. [provided by RefSeq
Other Designations
DNA directed RNA polymerase II 23 kda polypeptide|DNA directed RNA polymerase II polypeptide E|polymerase (RNA) II (DNA directed) polypeptide E (25kD)
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Interactome
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Pathway
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Disease
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