PSMA6 recombinant monoclonal antibody, clone R01-4I2
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More Files
- More Functions
Western Blot (Cell lysate)
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human PSMA6.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human PSMA6.
Theoretical MW (kDa)
27
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity chromatography
Isotype
IgG
Recommend Usage
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Cell lysate)
Immunocytochemistry
Immunofluorescence
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Gene Info — PSMA6
Entrez GeneID
5687Protein Accession#
P60900Gene Name
PSMA6
Gene Alias
IOTA, MGC22756, MGC2333, MGC23846, PROS27, p27K
Gene Description
proteasome (prosome, macropain) subunit, alpha type, 6
Omim ID
602855Gene Ontology
HyperlinkGene Summary
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome. [provided by RefSeq
Other Designations
27 kDa prosomal protein|OTTHUMP00000178843|macropain iota chain|macropain subunit iota|multicatalytic endopeptidase complex iota chain|prosomal P27K protein|proteasome alpha 6 subunit|proteasome iota chain|proteasome subunit iota
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Interactome
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Pathway
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Disease
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