TLR2 recombinant monoclonal antibody, clone TL2.1
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against immunising BALB/c mice with CHO cells transfected with human TLR2 cDNA.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to immunising BALB/c mice with CHO cells transfected with human TLR2 cDNA.
Reactivity
Human
Form
Liquid
Isotype
IgG
Recommend Usage
Blocking
Flow cytometry
Immunofluorescence
Immunoprecipitation
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% Proclin 300)
Storage Instruction
Store at 4°C for 3 months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunofluorescence
Immunofluorescence analysis of TLR2 (green) in K562 cells using human anti-TLR2 recombinant monoclonal antibody, clone TL2.1 (Cat # RAB03908), and DAPI(blue).Immunoprecipitation
Blocking
Flow Cytometry
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Gene Info — TLR2
Entrez GeneID
7097Protein Accession#
O60603Gene Name
TLR2
Gene Alias
CD282, TIL4
Gene Description
toll-like receptor 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. [provided by RefSeq
Other Designations
toll/interleukin 1 receptor-like 4
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Interactome
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Pathway
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Disease
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