LBR recombinant monoclonal antibody, clone R04-5H4
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human LBR.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human LBR.
Theoretical MW (kDa)
Calculated MW: 71 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:100)
Immunoprecipitation(1:20)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of K562 and Lane 2: Hela lysates with LBR recombinant monoclonal antibody, clone R04-5H4 (Cat # RAB02144).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin/PFA-fixed paraffin-embedded sections) of human lung cancer with LBR recombinant monoclonal antibody, clone R04-5H4 (Cat # RAB02144). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.Immunoprecipitation
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Gene Info — LBR
Entrez GeneID
3930Protein Accession#
Q14739Gene Name
LBR
Gene Alias
DHCR14B, FLJ43126, LMN2R, MGC9041, PHA
Gene Description
lamin B receptor
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000035631|integral nuclear envelope inner membrane protein
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Interactome
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