TERF2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant human TERF2.
Immunogen
Recombinant protein corresponding to amino acids of human TERF2.
Sequence
DIMQALLVRPLGKEHTVSRLLRVMQCLSRIEEGENLDCSFDMEAELTPLESAINVLEMIKTEFTLTEAVVESSRKLVKEAAVIICIKNKEFEKASKILKKHMSKDPTTQKLRNDLLNIIREKNLAHPVIQNF
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human pancreas with TERF2 polyclonal antibody (Cat# PAB29339) shows strong nuclear positivity in exocrine glandular cells.Immunofluorescence
Immunofluorescent staining of human cell line A-431 with TERF2 polyclonal antibody (Cat# PAB29339) under 1-4 ug/mL working concentration shows positivity in cytoplasm & nucleus but excluded from the nucleoli. -
Gene Info — TERF2
Entrez GeneID
7014Protein Accession#
Q15554Gene Name
TERF2
Gene Alias
TRBF2, TRF2
Gene Description
telomeric repeat binding factor 2
Omim ID
602027Gene Ontology
HyperlinkGene Summary
This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. [provided by RefSeq
Other Designations
telomeric repeat binding protein 2
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Interactome
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Disease
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