CD93 (Human) Recombinant Protein
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More Files
- More Functions
Enzyme-linked Immunoabsorbent Assay
Immobilized Human IGFBP-7, His Tag at 5 ug/mL (100 uL/well) on the plate. Dose response curve for Human CD93, hFc Tag with the EC50 of 1.10 ug/mL determined by ELISA.
SEC-HPLC
The purity of Human CD93 is greater than 95% as determined by SEC-HPLC.
Tris-Bis PAGE
Human CD93 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
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Specification
Product Description
Human CD93 (Q9NPY3, Thr22-Lys580) partial recombinant protein with hFc tag at C-terminus expressed in HEK293 cells.
Sequence
Thr22-Lys580
Host
Human
Theoretical MW (kDa)
85
Form
Lyophilized
Preparation Method
Mammalian cell (HEK293) expression system
Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin Level
< 1 EU per 1 ug of protein (determined by LAL method)
Activity
The EC50 was 1.10 ug/mL, messured by ELISA at 5 ug/mL.
Quality Control Testing
SEC-HPLC and Tris-Bis PAGE
SEC-HPLC
The purity of Human CD93 is greater than 95% as determined by SEC-HPLC.
Tris-Bis PAGE
Human CD93 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Recommend Usage
Biological Activity
ELISA
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from sterile distilled Water is > 100 ug/mL
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing.Note
Result of bioactivity analysis
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Applications
Enzyme-linked Immunoabsorbent Assay
Immobilized Human IGFBP-7, His Tag at 5 ug/mL (100 uL/well) on the plate. Dose response curve for Human CD93, hFc Tag with the EC50 of 1.10 ug/mL determined by ELISA.Functional Study
SDS-PAGE
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Gene Info — CD93
Entrez GeneID
22918Protein Accession#
Q9NPY3Gene Name
CD93
Gene Alias
C1QR1, C1qR(P), C1qRP, CDw93, MXRA4, dJ737E23.1
Gene Description
CD93 molecule
Omim ID
120577Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. [provided by RefSeq
Other Designations
C1q receptor 1|CD93 antigen|OTTHUMP00000030419|complement component 1, q subcomponent, receptor 1|matrix-remodelling associated 4
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Interactome
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Disease
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