MMP11 (Human) Recombinant Protein
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Specification
Product Description
Human MMP11 (NP_005931.1, 33 a.a. - 488 a.a.) partial recombinant protein with His-GST tag expressed in Escherichia coli.
Host
Escherichia coli
Theoretical MW (kDa)
79.817
Form
Liquid
Preparation Method
Escherichia coli expression system
Purity
> 80% by SDS-PAGE
Quality Control Testing
10% SDS-PAGE Stained with Coomassie Blue
Storage Buffer
In 20mM Sodium Phosphate, 0.5M NaCl, 0.15M imidazole, pH 7.4.
Storage Instruction
Store at -80°C.
Aliquot to avoid repeated freezing and thawing -
Applications
SDS-PAGE
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Gene Info — MMP11
Entrez GeneID
4320Protein Accession#
NP_005931.1Gene Name
MMP11
Gene Alias
SL-3, ST3, STMY3
Gene Description
matrix metallopeptidase 11 (stromelysin 3)
Omim ID
185261Gene Ontology
HyperlinkGene Summary
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq
Other Designations
matrix metalloproteinase 11|matrix metalloproteinase 11 (stromelysin 3)|stromelysin 3|stromelysin III
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Disease
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Publication Reference
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Diagnostic values of MMP-7, MMP-9, MMP-11, TIMP-1, TIMP-2, CEA, and CA19-9 in patients with colorectal cancer.
Xiwen Huang, Yongquan Lan, En Li, Jiaquan Li, Qiaoting Deng, Xunwei Deng.
The Journal of International Medical Research 2021 May; 49(5):3000605211.
Application：ELISA, Human, Human serum.
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Diagnostic values of MMP-7, MMP-9, MMP-11, TIMP-1, TIMP-2, CEA, and CA19-9 in patients with colorectal cancer.
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