IL20 (Human) Recombinant Protein
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Lane 1: non-reducing conditions
Lane 2: reducing conditions
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Specification
Product Description
Human IL20 (Q9NYY1) recombinant protein expressed in Escherichia coli.
Sequence
MLKTLNLGSCVIATNLQEIRNGFSEIRGSVQAKDGNIDIRILRRTESLQDTKPANRCCLLRHLLRLYLDRVFKNYQTPDHYTLRKISSLANSFLTIKKDLRLCHAHMTCHCGEEAMKKYSQILSHFEKLEPQAAVVKALGELDILLQWMEETE
Host
Escherichia coli
Theoretical MW (kDa)
35.2
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Endotoxin Level
< 0.1 EU/ug
Activity
The biological activity is determined by the ability to activate STAT following receptor ligand interaction.
Quality Control Testing
1 ug/lane in 4-20% Tris-Glycine gel Stained with Coomassie Blue
Lane 1: non-reducing conditions
Lane 2: reducing conditionsStorage Buffer
Lyophilized from 10 mM sodium citrate, 100 mM NaCl, pH 3.0
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with sterilized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — IL20
Entrez GeneID
50604Protein Accession#
Q9NYY1Gene Name
IL20
Gene Alias
IL-20, IL10D, MGC96907, ZCYTO10
Gene Description
interleukin 20
Omim ID
605619Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. [provided by RefSeq
Other Designations
OTTHUMP00000034617|OTTHUMP00000034618|four alpha helix cytokine
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