IL1R1 (Human) Recombinant Protein
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Specification
Product Description
Human IL1R1 (P14778, Lys 18 - Thr 332) partial recombinant protein expressed in 293 cells.
Host
Human
Theoretical MW (kDa)
55-60
Form
Lyophilized
Preparation Method
Mammalian cell (293) expression system
Purification
Ion exchange column and HPLC reverse phase column
Purity
> 90% by SDS-PAGE and HPLC
Endotoxin Level
< 0.1 ng/ug (1 EU/ug)
Activity
Measured by the ability to bind recombinant human Interleukin-1 beta.
Storage Buffer
Lyophilized from PBS solution, pH 7.2 (5% Trehalose)
Storage Instruction
Store at -20°C on dry atmosphere for 2 years.
After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 12 months.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — IL1R1
Entrez GeneID
3554Protein Accession#
P14778Gene Name
IL1R1
Gene Alias
CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80
Gene Description
interleukin 1 receptor, type I
Omim ID
147810Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. [provided by RefSeq
Other Designations
OTTHUMP00000161344|antigen CD121a|interleukin 1 receptor alpha, type I|interleukin receptor 1
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