CD36 monoclonal antibody, clone TR9 (APC)
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Specification
Product Description
Mouse monoclonal antibody raised against native CD36.
Immunogen
Native purified CD36 from human platelets.
Host
Mouse
Theoretical MW (kDa)
85
Reactivity
Human
Specificity
The antibody TR9 reacts with CD36 (GPIIIb), a 85 kDa integral membrane glycoprotein expressed on platelets, macrophages, endothelial cells, early erythroid cells and megakaryocytes. The antibody TR9 cross-blocks binding of FITC-labeled standard antibody OKM5.
Form
Liquid
Conjugation
APC
Purification
Size-exclusion chromatography purification
Isotype
IgG1
Recommend Usage
Flow Cytometry (10 uL reagent/100 uL of whole blood or 106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.02% BSA, 0.09% sodium azide)
Storage Instruction
Store in the dark at 4°C. Avoid prolonged exposure to light. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
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Gene Info — CD36
Entrez GeneID
948Gene Name
CD36
Gene Alias
CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3
Gene Description
CD36 molecule (thrombospondin receptor)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
CD36 antigen|CD36 antigen (collagen type I receptor, thrombospondin receptor)|PAS-4 protein|cluster determinant 36|fatty acid translocase|glycoprotein IIIb|leukocyte differentiation antigen CD36|platelet glycoprotein IV|scavenger receptor class B, member
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Interactome
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Disease
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