B3GAT1 monoclonal antibody, clone TB01
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Specification
Product Description
Mouse monoclonal antibody raised against native B3GAT1.
Immunogen
Native purified B3GAT1 from human neuroblastoma cells.
Host
Mouse
Reactivity
Human
Specificity
The monoclonal antibody recognizes the human CD57 molecule, expressed by NK cells and a subset of T cells.
Form
Liquid
Isotype
IgM
Recommend Usage
Immunohistochemistry (Frozen sections) (1:10-1:100)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:10-1:50)
Flow Cytometry (1:50-1:100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Frozen sections)
Flow Cytometry
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Gene Info — B3GAT1
Entrez GeneID
27087Gene Name
B3GAT1
Gene Alias
CD57, GLCATP, GlcAT-P, GlcUAT-P, HNK-1, HNK1, LEU7, NK-1
Gene Description
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
Omim ID
151290Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the glucuronyltransferase gene family. These enzymes exhibit strict acceptor specificity, recognizing nonreducing terminal sugars and their anomeric linkages. This gene product functions as the key enzyme in a glucuronyl transfer reaction during the biosynthesis of the carbohydrate epitope HNK-1 (human natural killer-1, also known as CD57 and LEU7). Alternate transcriptional splice variants have been characterized. [provided by RefSeq
Other Designations
CD57 antigen|LEU7 antigen|UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase|beta-1,3-glucuronyltransferase 1|galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1|glucuronosyltransferase P
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Interactome
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Pathway
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