ICAM2 monoclonal antibody, clone 7A6E11
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human ICAM2.
Immunogen
Recombinant protein corresponding to amino acids 25-223 of human ICAM2.
Host
Mouse
Theoretical MW (kDa)
30.7
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: ICAM2-hIgGFc transfected HEK293 cell lysates with ICAM2 monoclonal antibody, clone 7A6E11 (Cat # MAB17987).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with ICAM2 monoclonal antibody, clone 7A6E11 (Cat # MAB17987).Flow Cytometry
Flow cytometric analysis of Ramos cells with ICAM2 monoclonal antibody, clone 7A6E11 (Cat # MAB17987) (Green). Red: Negative Control. -
Gene Info — ICAM2
Entrez GeneID
3384Protein Accession#
P13598Gene Name
ICAM2
Gene Alias
CD102
Gene Description
intercellular adhesion molecule 2
Omim ID
146630Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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