CD3 monoclonal antibody, clone UCHT1 (FITC)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Flow Cytometry
Flow cytometric analysis of human peripheral blood lymphocytes using CD3 monoclonal antibody, clone UCHT1 (FITC) (Cat # MAB12204) compared to a relevant isotype control in red.
-
Specification
Product Description
Mouse monoclonal antibody raised against CD3.
Immunogen
Native purified CD3 from human thymocytes followed by Sezary T cells.
Host
Mouse
Reactivity
Human
Specificity
The clone UCHT1 monoclonal antibody reacts with human CD3e.
Form
Liquid
Conjugation
FITC
Purification
Affinity Chromatography
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.2 (0.09% Sodium azide, may contain carrier protein/stabilizer).
Storage Instruction
Store in the dark at 4°C. Avoid prolonged exposure to light. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Flow Cytometry
Flow cytometric analysis of human peripheral blood lymphocytes using CD3 monoclonal antibody, clone UCHT1 (FITC) (Cat # MAB12204) compared to a relevant isotype control in red. -
Gene Info — CD3E
Entrez GeneID
916Gene Name
CD3E
Gene Alias
FLJ18683, T3E, TCRE
Gene Description
CD3e molecule, epsilon (CD3-TCR complex)
Omim ID
186830Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq
Other Designations
CD3-epsilon|CD3E antigen, epsilon polypeptide|CD3e antigen, epsilon polypeptide (TiT3 complex)|T-cell antigen receptor complex, epsilon subunit of T3|T-cell surface antigen T3/Leu-4 epsilon chain|T-cell surface glycoprotein CD3 epsilon chain
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Downregulation of neuropilin-1 on macrophages modulates antibody-mediated tumoricidal activity.
Kawaguchi K, Suzuki E, Nishie M, Kii I, Kataoka TR, Hirata M, Inoue M, Pu F, Iwaisako K, Tsuda M, Yamaguchi A, Haga H, Hagiwara M, Toi M.
Cancer Immunology, Immunotherapy : CII 2017 Sep; 66(9):1131.
Application：Flow Cyt, Human, PBMCs.
-
Downregulation of neuropilin-1 on macrophages modulates antibody-mediated tumoricidal activity.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com