BMPR2 monoclonal antibody, clone 3F6
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis using BMPR2 monoclonal antibody, clone 3F6 (Cat # MAB10610) against HeLa (1) , A-431 (2) , NIH/3T3 (3) , COS-7 (4) and PC-12 (5) cell lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human muscle tissues (upper) and kidney cancer tissues (bottom) using BMPR2 monoclonal antibody, clone 3F6 (Cat # MAB10610) with DAB staining.
Immunofluorescence
Immunofluorescence analysis of Eca109 cells using BMPR2 monoclonal antibody, clone 3F6 (Cat # MAB10610) (green) . Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Enzyme-linked Immunoabsorbent Assay
ELISA measurement of BMPR2 monoclonal antibody, clone 3F6 (Cat # MAB10610) .
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Specifications
Product Description
Mouse monoclonal antibody raised against partial recombinant BMPR2.
Immunogen
Recombinant protein corresponding to amino acids 27-150 of human BMPR2.
Host
Mouse
Theoretical MW (kDa)
115
Reactivity
Human, Monkey, Mouse, Rat
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
Immunofluorescence (1:200-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis using BMPR2 monoclonal antibody, clone 3F6 (Cat # MAB10610) against HeLa (1) , A-431 (2) , NIH/3T3 (3) , COS-7 (4) and PC-12 (5) cell lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human muscle tissues (upper) and kidney cancer tissues (bottom) using BMPR2 monoclonal antibody, clone 3F6 (Cat # MAB10610) with DAB staining.Immunofluorescence
Immunofluorescence analysis of Eca109 cells using BMPR2 monoclonal antibody, clone 3F6 (Cat # MAB10610) (green) . Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.Enzyme-linked Immunoabsorbent Assay
ELISA measurement of BMPR2 monoclonal antibody, clone 3F6 (Cat # MAB10610) . -
Gene Info — BMPR2
Entrez GeneID
659Gene Name
BMPR2
Gene Alias
BMPR-II, BMPR3, BMR2, BRK-3, FLJ41585, FLJ76945, PPH1, T-ALK
Gene Description
bone morphogenetic protein receptor, type II (serine/threonine kinase)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq
Other Designations
BMP type II receptor|bone morphogenetic protein receptor type II|bone morphogenetic protein receptor type-2|primary pulmonary hypertension 1|serine/threonine kinase|type II activin receptor-like kinase|type II receptor for bone morphogenetic protein-4
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Interactomes
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Pathways
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Diseases
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