PON1 (Human) ELISA Kit
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Specification
Product Description
PON1 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human PON1.
Suitable Sample
Cell Culture Supernatants, Cell Lysates, Plasma (Heparin), Serum.
Sample Volume
100 uL
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
31.2 to 2000 pg/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Quality Control Testing
Standard Curve
The standard curve is for the purpose of demonstration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.
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Applications
Quantification
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Gene Info — PON1
Entrez GeneID
5444Gene Name
PON1
Gene Alias
ESA, PON
Gene Description
paraoxonase 1
Omim ID
168820Gene Ontology
HyperlinkGene Summary
The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3. [provided by RefSeq
Other Designations
arylesterase B-type|esterase A|paraoxonase B-type|serum aryldiakylphosphatase
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Interactome
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Pathway
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Disease
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Publication Reference
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Blb-NRF2-PON1 Cross-Talk in Abdominal Aortic Aneurysm Progression.
Magdalena P Kasprzak, Bogna Gryszczyńska, Anna Olasińska-Wiśniewska, Tomasz Urbanowicz, Andrzej Jawień, Zbigniew Krasiński, Dorota Formanowicz.
Antioxidants 2023 Aug; 12(8):1568.
Application:ELISA, Human, Human blood.
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Paraoxonase 1 Q192R genotype and activity affect homocysteine thiolactone levels in humans.
Perła-Kaján J, Borowczyk K, Głowacki R, Nygård O, Jakubowski H.
FASEB Journal 2018 May; [Epub].
Application:S-ELISA, Human, Plasma.
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Blb-NRF2-PON1 Cross-Talk in Abdominal Aortic Aneurysm Progression.
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