C1Q (Human) ELISA Kit
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Specifications
Product Description
C1Q (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human complement C1Q.
Suitable Sample
Cell Culture Samples, CSF, Milk, Plasma, Saliva, Serum, Urine
Sample Volume
50 uL
Label
Peroxidase-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
0.156 to 10 ng/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store components of the kit at 4°C or -20°C as described in the protocol.
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Applications
Quantification
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Gene Info — C1QA
Entrez GeneID
712Gene Name
C1QA
Gene Alias
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Gene Description
complement component 1, q subcomponent, A chain
Omim ID
120550Gene Ontology
HyperlinkGene Summary
This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the A-chain polypeptide of human complement subcomponent C1q. [provided by RefSeq
Other Designations
OTTHUMP00000002936|complement component 1, q subcomponent, alpha polypeptide|complement component C1q, A chain
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Gene Info — C1QB
Entrez GeneID
713Gene Name
C1QB
Gene Alias
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Gene Description
complement component 1, q subcomponent, B chain
Omim ID
120570Gene Ontology
HyperlinkGene Summary
This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the B-chain polypeptide of human complement subcomponent C1q [provided by RefSeq
Other Designations
OTTHUMP00000002940|complement component 1, q subcomponent, beta polypeptide|complement component C1q, B chain|complement subcomponent C1q chain B
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Gene Info — C1QC
Entrez GeneID
714Gene Name
C1QC
Gene Alias
C1Q-C, C1QG, FLJ27103
Gene Description
complement component 1, q subcomponent, C chain
Omim ID
120575Gene Ontology
HyperlinkGene Summary
This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000002932|OTTHUMP00000002933|OTTHUMP00000037922|complement C1q subcomponent subunit C|complement component 1, q subcomponent, gamma polypeptide
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Interactomes
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Pathways
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Diseases
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Publication Reference
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Systems immunology reveals a linked IgG3-C4 response in patients with acute rheumatic fever.
Chung AW, Ho TK, Hanson-Manful P, Tritscheller S, Raynes JM, Whitcombe AL, Tay ML, McGregor R, Lorenz N, Oliver JR, Gurney JK, Print CG, Wilson NJ, Martin WJ, Williamson DA, Baker MG, Moreland NJ.
Immunology and Cell Biology 2020 Jan; 98(1):12.
Application:Quant, Human, Human plasma.
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Systems immunology reveals a linked IgG3-C4 response in patients with acute rheumatic fever.
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