PDGFB (Human) Cell-Based ELISA Kit
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Specification
Product Description
PDGFB (Human) Cell-Based ELISA Kit is an indirect enzyme-linked immunoassay for qualitative determination of PDGFB expression in cultured cells.
Suitable Sample
Attached Cell, Loosely Attached Cell, Suspension Cell
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Qualitative
Reactivity
Human, Mouse, Rat
Regulation Status
For research use only (RUO)
Storage Instruction
Store the kit at 4°C.
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Applications
Qualitative
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Gene Info — PDGFB
Entrez GeneID
5155Gene Name
PDGFB
Gene Alias
FLJ12858, PDGF2, SIS, SSV, c-sis
Gene Description
platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
Omim ID
190040Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq
Other Designations
PDGF, B chain|Platelet-derived growth factor, beta polypeptide (oncogene SIS)|becaplermin|oncogene SIS|platelet-derived growth factor 2|platelet-derived growth factor beta|platelet-derived growth factor, B chain|v-sis platelet-derived growth factor beta p
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