SFRS12 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human SFRS12 protein.
Immunogen
SFRS12 (NP_631907.1, 1 a.a. ~ 508 a.a) full-length human protein.
Sequence
MTSLMPGAGLLPIPTPNPLTTLGVSLSSLGAIPAAALDPNIATLGEIPQPPLMGNVDPSKIDEIRRTVYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGDETQPTRFAFVEFADQNSVPRALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEENLSTKTEAV
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of SFRS12 expression in transfected 293T cell line (H00140890-T01) by SFRS12 MaxPab polyclonal antibody.
Lane1:SFRS12 transfected lysate(55.88 KDa).
Lane2:Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to SFRS12 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — SFRS12
Entrez GeneID
140890GeneBank Accession#
NM_139168.1Protein Accession#
NP_631907.1Gene Name
SFRS12
Gene Alias
DKFZp564B176, MGC133045, SRrp508, SRrp86
Gene Description
splicing factor, arginine/serine-rich 12
Omim ID
609268Gene Ontology
HyperlinkGene Summary
SFRS12 belongs to the superfamily of serine/arginine-rich (SR) splicing factors. It modulates splice site selection by regulating the activities of other SR proteins (Barnard et al., 2002 [PubMed 11991645]).[supplied by OMIM
Other Designations
OTTHUMP00000123466|serine-arginine-rich splicing regulatory protein 508
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Interactome
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Publication Reference
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Pathogenic SREK1 Decrease in Huntington's Disease Lowers TAF1 Mimicking X-linked Dystonia Parkinsonism.
Ivó H Hernández, Jorge R Cabrera, María Santos-Galindo, Manuel Sánchez-Martín, Verónica Domínguez, Ramón García-Escudero, María J Pérez-Álvarez, Belén Pintado, José J Lucas.
Brain 2020 Jul; 143(7):2207.
Application:IHC, WB-Ce, WB-Ti, Human, Mouse, SH-SY5Y cells, Brain.
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Pathogenic SREK1 Decrease in Huntington's Disease Lowers TAF1 Mimicking X-linked Dystonia Parkinsonism.
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