LIAS monoclonal antibody (M03), clone 1C7

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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant LIAS.
Immunogen
LIAS (NP_006850, 273 a.a. ~ 372 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ISKTSIMLGLGENDEQVYATMKALREADVDCLTLGQYMQPTRRHLKVEEYITPEKFKYWEKVGNELGFHYTASGPLVRSSYKAGEFFLKNLVAKRKTKDL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (87); Rat (87)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to LIAS on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 1.2 ug/ml]ELISA
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Gene Info — LIAS
Entrez GeneID
11019GeneBank Accession#
NM_006859Protein Accession#
NP_006850Gene Name
LIAS
Gene Alias
HUSSY-01, LAS, LIP1, MGC23245
Gene Description
lipoic acid synthetase
Omim ID
607031Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq
Other Designations
lipoate synthase
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Interactome
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Pathway
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