NPC2 purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human NPC2 protein.
Immunogen
NPC2 (NP_006423.1, 1 a.a. ~ 151 a.a) full-length human protein.
Sequence
MRFLAATFLLLALSTAAQAEPVQFKDCGSVDGVIKEVNVSPCPTQPCQLSKGQSYSVNVTFTSNIQSKSSKAVVHGILMGVPVPFPIPEPDGCKSGINCPIQKDKTYSYLNKLPVKSEYPSIKLVVEWQLQDDKNQSLFCWEIPVQIVSHL
Host
Mouse
Reactivity
Human, Mouse
Interspecies Antigen Sequence
Mouse (81); Rat (80)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
NPC2 MaxPab polyclonal antibody. Western Blot analysis of NPC2 expression in NIH/3T3.Western Blot (Transfected lysate)
Western Blot analysis of NPC2 expression in transfected 293T cell line (H00010577-T01) by NPC2 MaxPab polyclonal antibody.
Lane 1: NPC2 transfected lysate(16.61 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — NPC2
Entrez GeneID
10577GeneBank Accession#
NM_006432.3Protein Accession#
NP_006423.1Gene Name
NPC2
Gene Alias
HE1, MGC1333, NP-C2
Gene Description
Niemann-Pick disease, type C2
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy. [provided by RefSeq
Other Designations
epididymal secretory protein|epididymal secretory protein E1|tissue-specific secretory protein
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Interactome
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Disease
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Publication Reference
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Comparative analysis of the seminal plasma proteomes of oligoasthenozoospermic and normozoospermic men.
Giacomini E, Ura B, Giolo E, Luppi S, Martinelli M, Garcia RC, Ricci G.
Reproductive Biomedicine Online 2015 May; 30(5):522.
Application:WB, Human, Plasma.
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Comparative analysis of the seminal plasma proteomes of oligoasthenozoospermic and normozoospermic men.
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