SIRPB1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human SIRPB1 full-length ORF ( AAH75835.1, 1 a.a. - 181 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MPVPASWPHLPSPFLLMTLLLGRLTGVAGEDELQVIQPEKSVSVAAGESATLRCAMTSLIPVGPIMWFRGAGAGRELIYNQKEGHFPRVTTVSELTKRNNLDFSISISNITPADAGTYYCVKFRKGSPDDVEFKSGAGTELSVREPALAPTAPLLVALLLGPKLLLVVGVSAIYICWKQKA
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
45.8
Interspecies Antigen Sequence
Mouse (51)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SIRPB1
Entrez GeneID
10326GeneBank Accession#
BC075835.1Protein Accession#
AAH75835.1Gene Name
SIRPB1
Gene Alias
CD172b, DKFZp686A05192, FLJ26614, SIRP-BETA-1
Gene Description
signal-regulatory protein beta 1
Omim ID
603889Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000029992|OTTHUMP00000029993
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