MSX2 monoclonal antibody (M04), clone 1F6

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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MSX2.
Immunogen
MSX2 (NP_002440, 101 a.a. ~ 201 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
TASVKSENSEDGAAWMQEPGRYSPPPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRL*
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to MSX2 on formalin-fixed paraffin-embedded human testis. [antibody concentration 1.5 ug/ml]ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to MSX2 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — MSX2
Entrez GeneID
4488GeneBank Accession#
NM_002449Protein Accession#
NP_002440Gene Name
MSX2
Gene Alias
CRS2, FPP, HOX8, MSH, PFM, PFM1
Gene Description
msh homeobox 2
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. [provided by RefSeq
Other Designations
msh homeo box 2|msh homeobox homolog 2
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Interactome
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Disease
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Publication Reference
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Establishment of human dental epithelial cell lines expressing ameloblastin and enamelin by transfection of hTERT and cdk4 cDNAs.
Hatakeyama S, Mizusawa N, Tsutsumi R, Yoshimoto K, Mizuki H, Yasumoto S, Sato S, Takeda Y.
Journal of Oral Pathology & Medicine 2011 Mar; 40(3):227.
Application:IF, Human, HAM2 cells.
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Establishment of human dental epithelial cell lines expressing ameloblastin and enamelin by transfection of hTERT and cdk4 cDNAs.
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