GSN 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specifications
Transfected Cell Line
293T
Plasmid
pCMV-GSN full-length
Host
Human
Theoretical MW (kDa)
86.13
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-GSN antibody (H00002934-B01) by Western Blots.
SDS-PAGE Gel
GSN transfected lysate.
Western Blot
Lane 1: GSN transfected lysate ( 86.13 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — GSN
Entrez GeneID
2934GeneBank Accession#
NM_000177.4Protein Accession#
AAH26033.1Gene Name
GSN
Gene Alias
DKFZp313L0718
Gene Description
gelsolin (amyloidosis, Finnish type)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000022011|OTTHUMP00000162202|gelsolin
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Interactomes
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Pathways
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Diseases
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