GABPA monoclonal antibody (M04), clone 1D6
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant GABPA.
Immunogen
GABPA (NP_002031, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MTKREAEELIEIEIDGTEKAECTEESIVEQTYAPAECVSQAIDINEPIGNLKKLLEPRLQCSLDAHEICLQDIQLDPERSLFDQGVKTDGTVQLSVQVIS
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
GABPA monoclonal antibody (M04), clone 1D6 Western Blot analysis of GABPA expression in Hela S3 NE ( Cat # L013V3 ).Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to GABPA on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml]ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to GABPA on HeLa cell. [antibody concentration 40 ug/ml] -
Gene Info — GABPA
Entrez GeneID
2551GeneBank Accession#
NM_002040Protein Accession#
NP_002031Gene Name
GABPA
Gene Alias
E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A
Gene Description
GA binding protein transcription factor, alpha subunit 60kDa
Omim ID
600609Gene Ontology
HyperlinkGene Summary
This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. [provided by RefSeq
Other Designations
GA binding protein transcription factor, alpha subunit|OTTHUMP00000096114|human nuclear respiratory factor-2 subunit alpha|nuclear respiratory factor 2 alpha subunit
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Interactome
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Disease
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