ALDH1A1 MaxPab rabbit polyclonal antibody (D01)
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human ALDH1A1 protein.
Immunogen
ALDH1A1 (NP_000680.2, 1 a.a. ~ 501 a.a) full-length human protein.
Sequence
MSSSGTPDLPVLLTDLKIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKISQKNS
Host
Rabbit
Reactivity
Human, Mouse
Interspecies Antigen Sequence
Mouse (87); Rat (86)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
ALDH1A1 MaxPab rabbit polyclonal antibody. Western Blot analysis of ALDH1A1 expression in mouse liver.Western Blot (Tissue lysate)
ALDH1A1 MaxPab rabbit polyclonal antibody. Western Blot analysis of ALDH1A1 expression in human liver.Western Blot (Tissue lysate)
ALDH1A1 MaxPab rabbit polyclonal antibody. Western Blot analysis of ALDH1A1 expression in mouse lung.Western Blot (Cell lysate)
ALDH1A1 MaxPab rabbit polyclonal antibody. Western Blot analysis of ALDH1A1 expression in K-562.Western Blot (Cell lysate)
ALDH1A1 MaxPab rabbit polyclonal antibody. Western Blot analysis of ALDH1A1 expression in HepG2.Western Blot (Transfected lysate)
Western Blot analysis of ALDH1A1 expression in transfected 293T cell line (H00000216-T01) by ALDH1A1 MaxPab polyclonal antibody.
Lane 1: ALDH1A1 transfected lysate(54.9 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of ALDH1A1 transfected lysate using anti-ALDH1A1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with ALDH1A1 purified MaxPab mouse polyclonal antibody (B01P) (H00000216-B01P). -
Gene Info — ALDH1A1
Entrez GeneID
216GeneBank Accession#
NM_000689.3Protein Accession#
NP_000680.2Gene Name
ALDH1A1
Gene Alias
ALDC, ALDH-E1, ALDH1, ALDH11, MGC2318, PUMB1, RALDH1
Gene Description
aldehyde dehydrogenase 1 family, member A1
Gene Ontology
HyperlinkGene Summary
This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a cytosolic isoform, which has a high affinity for aldehydes. [provided by RefSeq
Other Designations
ALDH class 1|acetaldehyde dehydrogenase 1|aldehyde dehydrogenase 1, soluble|aldehyde dehydrogenase 1A1|aldehyde dehydrogenase, liver cytosolic|retinal dehydrogenase 1|retinaldehyde dehydrogenase 1
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Interactome
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Disease
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