TFPI polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TFPI.
Immunogen
A synthetic peptide corresponding to 13 amino acids at N-terminus of human TFPI.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
TFPI antibody is human, mouse and rat reactive. At least two isoforms of TFPI are known to exist; this antibody will detect both isoforms.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Isotype
IgG
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of TFPI in rat small intestine tissue with TFPI polyclonal antibody (Cat # PAB27453) at 1 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — TFPI
Entrez GeneID
7035Protein Accession#
NP_006278Gene Name
TFPI
Gene Alias
EPI, LACI, TFI, TFPI1
Gene Description
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
Omim ID
152310Gene Ontology
HyperlinkGene Summary
This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed. [provided by RefSeq
Other Designations
OTTHUMP00000163472|anti-convertin|extrinsic pathway inhibitor|lipoprotein-associated coagulation inhibitor|tissue factor pathway inhibitor
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Interactome
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Pathway
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