FASLG monoclonal antibody, clone SB93a
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specifications
Product Description
Mouse monoclonal antibody raised against recombinant FASLG.
Immunogen
Recombinant protein corresponding to human TNFSF10.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
Flow Cytometry (1 ug/106 cells
Western Blot (0.5-2 ug/mL)
Immunoprecipitation (5-20 ug)
The optimal working dilution should be determined by the end user.Storage Buffer
In 100 mM BBS, pH 8.0
Storage Instruction
Store at 4°C.
-
Applications
Western Blot
Immunoprecipitation
Flow Cytometry
Human PBMC stimulated with (red line) orwithout (dotted line) PMA/ionomycin, thenblocked with an MMP7 inhibitor. Cells werethen stained with FASLG monoclonal antibody, clone SB93a-FITC at 1 ug/mL dilution. -
Gene Info — FASLG
Entrez GeneID
356Gene Name
FASLG
Gene Alias
APT1LG1, CD178, CD95L, FASL, TNFSF6
Gene Description
Fas ligand (TNF superfamily, member 6)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the ligand for FAS. Both are transmembrane proteins. Interaction of FAS with this ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). [provided by RefSeq
Other Designations
CD95 ligand|OTTHUMP00000032708|apoptosis (APO-1) antigen ligand 1|fas ligand|tumor necrosis factor (ligand) superfamily, member 6
-
Interactomes
-
Pathways
-
Diseases
-
Publication Reference
-
Posttranslational regulation of Fas ligand function.
Voss M, Lettau M, Paulsen M, Janssen O.
Cell Communication and Signaling 2008 Dec; 6:11.
-
Delivering the kiss of death.
Trambas CM, Griffiths GM.
Nature Immunology 2003 May; 4(5):399.
-
CD95's deadly mission in the immune system.
Krammer PH.
Nature 2000 Oct; 407(6805):789.
Application:ELISA, Human, Immune cells, Serum.
-
Posttranslational regulation of Fas ligand function.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com